产品货号：
Z18283
中文名称：
IL-1 beta/IL1B抗体
英文名称：
Anti-IL-1 beta/IL1B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL-1 beta/IL1B Antibody |
| 指标别名 | IL1 beta;Catabolin;IL 1;IL 1 beta;IL1 BETA;IL-1 beta;IL1- beta;IL1B;IL1beta;IL1F2;IL-1β;Interleukin 1 beta;interleukin 1;beta;Pro IL-1β;IL 1B;IL-1B |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | WB,ELISA |
| 基因名称 | Il1b |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse IL-1 beta/Il1b recombinant protein (Position:V118-S269). |
| 实际分子量 | 36KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Interleukin-1β (IL-1β) is a potent stimulator of bone resorption whose gene is mapped to 2q14,and has been implicated in the pathogenesis of high bone turnover and osteoporosis.IL-1β,a prominent microglia-derived cytokine,caused oligodendrocyte death in coculture with astrocytes and microglia,but not in pure culture of oligodendrocytes alone.It also can cause nuclear export of a specific NCOR corepressor complex,resulting in derepression of a specific subset of nuclear factor-kappa-B (NFKB)-regulated genes.Furthermore,Microenvironmental IL-1β and,to a lesser extent,IL-1α are required for in vivo angiogenesis and invasiveness of different tumor cells.Additional,the cooperation of IL-1β and PDGFB induces contractile-to-synthetic phenotype modulation of human aortic smooth muscle cells in culture.Moreover,the association with disease may be explained by the biologic properties of IL-1β,which is an important proinflammatory cytokine and a powerful inhibitor of gastric acid secretion. |
| Uniprot ID | P10749 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 ELISA： 1:100～1000 |
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